解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::After partial (spared-root) or complete hindlimb deafferentation, locomotion and accurate limb placement during locomotion recover considerably. In the present study movement was studied during and after recovery to determine whether altered motor patterns could substitute for normal ones in the recovery of motor beha...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00248226
更新日期:1988-01-01 00:00:00
abstract::Receptive field (RF) characteristics of cells in primary visual cortex of the mouse (C57B16 strain) were studied by single unit recording. We have studied the functional organization of area 17 along both the radial and tangential dimensions of the cortex. Eighty seven percent of the visual neurons could be classified...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00247312
更新日期:1988-01-01 00:00:00
abstract::We compared set-related premotor cortex activity in two conditional motor tasks. In both tasks, a rhesus monkey moved its forelimb to one of two possible targets on the basis of visuospatial instruction stimuli. One target was located to the left of the limb's starting position, the other to the right. In the directio...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00247578
更新日期:1988-01-01 00:00:00
abstract::We examined opioid binding in fractions with disconnected nerve endings (secretosomes) which were prepared from porcine neurohypophyses by centrifugation in a discontinuous Percoll gradient. Specific (= displaceable) binding was observed with 3H-etorphine and with 3H-diprenorphine, two ligands with low selectivity for...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00271856
更新日期:1988-01-01 00:00:00
abstract::The tectofugal pathway in birds has been reported to process primarily information from the contralateral eye. Although this pathway has access to the contralateral hemisphere by various connections, electrophysiological recordings up to now have failed to demonstrate any excitatory influence of visual stimulation in ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00271850
更新日期:1988-01-01 00:00:00
abstract::In one of the most-widely used species in pineal gland research, the strongly photoperiodic golden hamster, Mesocricetus auratus, no electrophysiological data on pinealocytes are currently available. To fill this gap, in the present study 185 spontaneously active pinealocytes from male golden hamsters were recorded ex...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00269449
更新日期:1987-01-01 00:00:00
abstract::We investigated a double-label 2-DG protocol and method of analysis in which sequential injections of 3H- and 14C-2-DG were used to map brain metabolism during two distinct experimental treatments in the same animal. In initial studies, brain sections from rats given only 3H-2-DG or only 14C-2-DG were exposed on Ultro...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00270687
更新日期:1987-01-01 00:00:00
abstract::The specificity of adaptation of vestibulo-ocular reflex direction was examined by exposing cats to combined pitch vestibular rotation and horizontal optokinetic motion at 0.25 Hz, while alternating body position between lying on the left side and lying on the right. The direction of optokinetic motion relative to hea...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00247045
更新日期:1987-01-01 00:00:00
abstract::Previous studies have shown that the "synaptic" bodies of mammalian pinealocytes are a heterogeneous group of organelles. Whereas "synaptic" ribbons (SR) exhibit a day/night rhythm with small numbers during daytime and high numbers at night, the so-called "synaptic" spherules (SS) show species-specific differences in ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00236214
更新日期:1987-01-01 00:00:00
abstract::The intracortical arborizations of thalamocortical fibers arising from the ventroposterolateral (VPL) nucleus in the cat were studied following intra-axonal injections of horseradish peroxidase (HRP). The axons were impaled 1.5 to 3 mm below the surface of the cortex, identified electrophysiologically by stimulating t...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00236304
更新日期:1987-01-01 00:00:00
abstract::In an attempt to identify cholinergic neurons of the brain stem which project to the forebrain, retrograde labeling of neurons in the brain stem was examined by autoradiography following injections of 20 microCi [3H]choline into the thalamus, hypothalamus, basal forebrain and frontal cortex. After injections into the ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00236317
更新日期:1987-01-01 00:00:00
abstract::Dispersed brain cells from 12-14 day old mouse embryos were loaded with the Ca2+-sensitive fluorescent probe, quin2 and shown to have a resting intracellular Ca2+ concentration ([Ca2+]i) of 158 nM (SE +/- 5) in the presence of 1 mM [Ca2+]o. When external [Ca2+] was raised from 0 to 1 mM there was an increase of [Ca2+]...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00235975
更新日期:1987-01-01 00:00:00
abstract::The fate of monoclonal anti-vasopressin antibodies (VP-MAbs) injected in vivo into the paraventricular nucleus (PVN) of the rat brain was studied by immunocytochemistry. Depending on the post survival time, VP-MAbs contained in an ascites fluid were stained at different levels of the VP neurons: the cytoplasm of the P...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00235986
更新日期:1987-01-01 00:00:00
abstract::The latencies of visually-evoked responses from X- and Y-type neurons of the cat's dorsal lateral geniculate nucleus were measured in a manner that takes account of the inherent variability of discharge in these cells. Latencies measured in this way vary from trial to trial in one cell (and also between cells) by tens...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00235998
更新日期:1987-01-01 00:00:00
abstract::Single neurons in the auditory cortex of anesthetized cats were examined quantitatively for their sensitivity to the sound pressure level of characteristic frequency (CF) tone pulses, and to 6 dB, linear modulations in the amplitude of a continuous CF carrier tone. The direction and rate of amplitude modulation (AM), ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00247281
更新日期:1987-01-01 00:00:00
abstract::Single cell activity was recorded from the putamen in rhesus monkeys (Macaca mulatta) performing limb movements made both with and without a preceding preparatory "set" concerning the impending direction of movement. The monkeys were trained to perform an elbow step-tracking task, each trial of which required the subj...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00247293
更新日期:1987-01-01 00:00:00
abstract::The experiments were designed to test two hypotheses and their corollaries: 1. That adaptation of EMG responses to support surface rotations is due to a decrease in the gain of proprioceptively triggered long-loop stretch reflexes (Nashner 1976), and that the adaptation is dependent on a normally functioning vestibula...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00247031
更新日期:1987-01-01 00:00:00
abstract::Chemoreceptor pathways from the vomeronasal organ (VNO), and main olfactory system are known to be separate as they pass into the brain, at least until the level of the amygdala. In the amygdala, vomeronasal pathways project to the posteromedial cortical nucleus (PMCN), and medial nucleus (MN). The main olfactory path...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00247024
更新日期:1987-01-01 00:00:00
abstract::Dopamine and somatostatin-14 (SRIF) were incubated with a membrane fraction of rat caudate-putamen (CP) tissue in an adenylate cyclase assay in order to examine the D-1-receptor coupled adenylate cyclase activity 5 days and 3 weeks after unilateral ablation of the left frontal and lateral cortex. Five days after decor...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00248805
更新日期:1987-01-01 00:00:00
abstract::The fluorescent double-labeling technique has been used to determine whether the corticopontine and the corticotectal fibers in the cat are derived from two different sets of neurons or whether they are derived from branching neurons which distribute collaterals to the pontine grey and the colliculi. After unilateral ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00269447
更新日期:1987-01-01 00:00:00
abstract::We applied vibration at various rates to the biceps tendon of a passive, restrained arm in normal human subjects and measured its effect on the perception of forearm position and the perception of forearm velocity. The disturbances of limb position perception and limb velocity perception depended on the vibration rate...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00269450
更新日期:1987-01-01 00:00:00
abstract::The course and cerebellar termination of the axons of the cells in the central cervical nucleus (CCN) was studied in five cats after injections of wheat germ agglutinin-horseradish peroxidase conjugate (WGA-HRP) into the C1-4 segments involving the CCN. In two cats a hemisection was performed ipsilateral to and above ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00248549
更新日期:1987-01-01 00:00:00
abstract::Slow eye movements were observed while the monkey fixated on a subject-stationary, small target light in front of a moving optokinetic drum in an attempt to suppress optokinetic nystagmus (OKN). These slow eye movements of low amplitude were directed opposite to the moving optokinetic stimulus and, hence, were not ide...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00248564
更新日期:1987-01-01 00:00:00
abstract::Saslow and others have shown that the latency of foveating saccades can be altered by changing the offset time of the current fixation point relative to the onset of the peripheral target. Whether anticipatory saccades contributed to these results was not known. By the criteria of direction error and amplitude error t...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00255238
更新日期:1987-01-01 00:00:00
abstract::Previously we described physiological properties of pontine reticulo-spinal neurons which generate bursts and decaying tonic discharges related to eye movements and neck muscle activity during ipsiversive gaze shifts (Grantyn and Berthoz 1987). Two of these "eye-neck reticulo-spinal neurons" (EN-RSN) were labeled by i...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00243310
更新日期:1987-01-01 00:00:00
abstract::We have tested the hypothesis that complex cell receptive fields are made up of subfields which, for a given cell, have either exclusively even or exclusively odd symmetry. To do this we have measured the response of complex cells in the visual cortex of the cat to members of pairs of spatially limited even-symmetric ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00248791
更新日期:1987-01-01 00:00:00
abstract::We have studied the ability of a quaternary antihistamine, thiazinamium, to inhibit the nociceptive sensitization that occurs early, during the first hour, following intraplantar injection of the polysaccharide carrageenin in the rat. Parallel studies were performed with an electrophysiological model (changes in respo...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00236307
更新日期:1987-01-01 00:00:00
abstract::1. Binaural neurones were recorded in the central nucleus of the cat inferior colliculus and were stimulated with tone and noise bursts. Closed field sound systems were used to produce independent interaural time (ITD) and intensity (IID) differences. Particular attention was paid to high frequency (above 2 kHz) cells...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00248803
更新日期:1987-01-01 00:00:00
abstract::The active components of the quadrupedal diagonal stance response to rapid removal of the support from beneath a single limb were studied in cats to further define the mechanisms that trigger and generate the response. We recorded EMG activity from lateral gastrocnemius and tibialis anterior muscles in awake, behaving...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00249792
更新日期:1987-01-01 00:00:00
abstract::In anesthetized and paralyzed cats, the normal alignment of the visual axes is disturbed by paralysis of the eye muscles. Thus, the separation between paired receptive fields of binocular cells in visual cortex is increased (paralysis squint). This increased separation is normally tolerated by the majority of visuocor...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00249802
更新日期:1987-01-01 00:00:00
abstract::Vasopressin and oxytocin immunoreactivity (AVP-IR, OT-IR) have been detected in the trigeminal and dorsal root ganglia (TG, DRG) of the rat. We have investigated whether AVP or OT have any neurotransmitter role in these tissues by measuring the effects of the peptides on levels of intracellular second messengers. AVP ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00248795
更新日期:1987-01-01 00:00:00
abstract::Electrical activity of neurons in rat hypothalamic ventromedial nucleus was recorded in tissue slices, to investigate central neural mechanisms underlying reduction of food intake caused by TRH and its metabolite, cyclo(His-Pro) [cHP]. Application of TRH had two actions: stimulation of neuronal activity, which was des...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00269457
更新日期:1987-01-01 00:00:00
abstract::Load perturbations were applied to the arm of human subjects under conditions where both limb segments (upper arm and forearm) were free to move. The perturbations consisted of pulses of torque 50 ms in duration and of pseudo-random sequences of such pulses. They were applied to either the forearm or the upper arm. Un...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237573
更新日期:1986-01-01 00:00:00
abstract::Morphometric changes have been studied at the mouse neuromuscular junction (NMJ) as a function of the frequency of stimulation. In vivo stimulation was made at either 10, 25, 50 or 100 Hz. No significant change in the area of NMJ profiles is observed after stimulation. This indicates that stimulation does not change t...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237590
更新日期:1986-01-01 00:00:00
abstract::Postural reactions to disruptions of stance are rapid and automatic in both quadrupeds and bipeds. Current evidence suggests that these postural responses are generated by the central nervous system as patterns involving muscle synergies. This study attempted to test this hypothesis of a centrally generated postural m...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237411
更新日期:1986-01-01 00:00:00
abstract::Control of velocity in rapid flexion movements of the interphalangeal joint of the thumb was investigated by examining movement trajectories and patterns of activity in the extensor pollicis longus (EPL) and flexor pollicis longus (FPL) muscles. Although velocity was controlled with considerable accuracy, it was not s...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237406
更新日期:1986-01-01 00:00:00
abstract::Fast goal-directed voluntary movements of the human upper extremity are known to be associated with three distinct bursts of EMG activity in antagonistic muscles. The role of each burst (AG1, ANT, AG2) in controlling motion is not fully understood, largely because overall limb response is a complex function of the ent...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00236850
更新日期:1986-01-01 00:00:00
abstract::Previous investigations have revealed that perceived spatial frequency of gratings rises as contrast is lowered. In order to account for this finding it has been postulated that the spatial frequency which produces the maximum response from cortical neurones decreases with contrast. We have examined this hypothesis by...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00236862
更新日期:1986-01-01 00:00:00
abstract::The present study analyses the strategies adopted by normal subjects when they are asked to make two separate movements as rapidly as possible one after the other. Five subjects performed the following sequential movements in their own time. 1) Squeeze an isometric force transducer between fingers and thumb to a force...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237481
更新日期:1986-01-01 00:00:00
abstract::Successive motor unit (MU) twitches often do not sum linearly. Also, muscle spindle (MS) afferents may react nonlinearly to MU contractions occurring at short intervals. Little data is presently available on the interactions between two (or more) MUs regarding their effects on tension output and MS responses. We have ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237486
更新日期:1986-01-01 00:00:00